Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24386362 | 0.84 | NPC1 (0.62) | RAB9ANPC1MEN1KMT2AHDAC8 | |
| SCHEMBL22400147 | 0.82 | TP53BP1 (0.58) | RAB9ANPC1MEN1KMT2AATM | |
| SCHEMBL1753828 | 0.79 | L3MBTL1 (0.71) | RAB9ANPC1MEN1KMT2AHDAC8 | |
| SCHEMBL9492626 | 0.79 | NPC1 (0.68) | RAB9ANPC1MEN1KMT2AHDAC8 | |
| SCHEMBL842631 | 0.79 | NPC1 (0.68) | RAB9ANPC1MEN1KMT2AHDAC8 | |
| SCHEMBL12678025 | 0.77 | NPC1 (0.66) | RAB9ANPC1MEN1KMT2AHDAC8 | |
| SCHEMBL14538231 | 0.77 | NPC1 (0.66) | RAB9ANPC1MEN1KMT2AHDAC8 | |
| SCHEMBL11234425 | 0.77 | RAB9A (0.66) | RAB9ANPC1MEN1KMT2AHDAC8 | |
| SCHEMBL13655554 | 0.77 | HDAC1 (0.57) | RAB9ANPC1HDAC8HDAC6 | |
| SCHEMBL12867 | 0.76 | NPC1 (0.64) | RAB9ANPC1MEN1KMT2AHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136689-A1 | PURINE COMPOUNDS POSSESSING ANTICANCER ACTIVITY | ACADEMIA SINICA (TW) | 2017-08-10 | — | — | WO | disclosed |