Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 3/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | SCN2B | O60939 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30744927 | 0.86 | NPSR1 (0.61) | LMNAMEN1KMT2ASCN9AMRGPRX4 | |
| SCHEMBL22503070 | 0.83 | ACHE (0.56) | HDAC8HDAC6LMNAACHENR1H4 | |
| SCHEMBL12201883 | 0.83 | HDAC8 (0.77) | HDAC8HDAC6ACHENR1H4HDAC3 | |
| SCHEMBL7990830 | 0.81 | HDAC1 (0.66) | HDAC8HDAC6LMNANR1H4HDAC3 | |
| SCHEMBL10120025 | 0.80 | HDAC8 (0.59) | HDAC8HDAC6ACHENR1H4HDAC3 | |
| SCHEMBL12949253 | 0.79 | LMNA (0.59) | HDAC8HDAC6LMNAACHENR1H4 | |
| SCHEMBL13698098 | 0.78 | ACHE (0.60) | HDAC8HDAC6ACHENR1H4HDAC3 | |
| SCHEMBL10197595 | 0.78 | HDAC8 (0.57) | HDAC8HDAC6LMNAACHENR1H4 | |
| SCHEMBL280256 | 0.78 | HDAC8 (0.68) | HDAC8HDAC6MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13331743 | 0.78 | KDM4E (0.65) | HDAC8HDAC6MEN1KMT2ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732078-B2 | Therapeutic use of imidazopyridine derivatives | SANOFI (FR) | 2017-08-15 | — | — | US | disclosed |