Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12503127 | 0.82 | DGAT1 (0.44) | DGAT1USP2SMN1; SMN2MAOAMAOB | |
| SCHEMBL14552607 | 0.81 | DGAT1 (0.35) | DGAT1HDAC6HDAC1HDAC2ELANE | |
| Hydrochloric Acid SCHEMBL16742421 | 0.80 | DGAT1 (0.43) | DGAT1USP2SMN1; SMN2MAOAMAOB | |
| Ethylenediamine SCHEMBL28140303 | 0.78 | HDAC6 (0.36) | DGAT1HDAC6HDAC1HDAC2USP2 | |
| Hydrochloric Acid SCHEMBL28096965 | 0.76 | SOAT1 (0.52) | KDM4E | |
| SCHEMBL1926432 | 0.76 | DGAT1 (0.38) | DGAT1HDAC6HDAC1HDAC2USP2 | |
| SCHEMBL10017912 | 0.75 | DGAT1 (0.41) | DGAT1HDAC6HDAC1HDAC2USP2 | |
| SCHEMBL1926065 | 0.75 | CYP2C19 (0.41) | ELANE | |
| SCHEMBL848847 | 0.74 | HDAC6 (0.34) | DGAT1HDAC6HDAC1HDAC2USP2 | |
| SCHEMBL8375577 | 0.74 | DGAT1 (0.42) | DGAT1HDAC6HDAC1HDAC2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114651000-A | Biocatalytic synthesis of nostoc anticancer agents | 密歇根大学董事会 | 2022-06-21 | — | — | CN | disclosed |
| EP-2509942-A2 | BIS-ACYLATED HYDROXYLAMINE DERIVATIVES | Johns Hopkins University (US) | 2012-10-17 | — | — | EP | disclosed |
| EP-2509941-A2 | N-ACYLATED HYDROXYLAMINE DERIVATIVES AND O-ACYLATED HYDROXYLAMINE DERIVATIVES | The Johns Hopkins University (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011071947-A2 | BIS-ACYLATED HYDROXYLAMINE DERIVATIVES | JOHNS HOPKINS UNIVERSITY (US) | 2011-06-16 | — | — | WO | disclosed |
| WO-2011071951-A2 | N-ACYLOXYSULFONAMIDE AND N-HYDROXY-N-ACYLSULFONAMIDE DERIVATIVES | JOHNS HOPKINS UNIVERSITY (US) | 2011-06-16 | — | — | WO | disclosed |