SCHEMBL848847

SCHEMBL848847

CC(C)(C)OC(=O)OC(=O)CN

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 2/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC2 Q92769 1/20 0.34
ELANE P08246 1/20 0.33
DGAT1 O75907 1/20 0.32
CA12 O43570 1/20 0.31
CA2 P00918 1/20 0.31
CA14 Q9ULX7 1/20 0.31
USP2 O75604 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9299514 0.98 HDAC6 (0.33) HDAC6HDAC1HDAC2ELANEDGAT1
SCHEMBL1827760 0.83 HDAC6 (0.36) HDAC6HDAC1HDAC2ELANEDGAT1
SCHEMBL27804594 0.82 HDAC6 (0.37) HDAC6HDAC1HDAC2
Ethylenediamine SCHEMBL28140303 0.81 HDAC6 (0.36) HDAC6HDAC1HDAC2ELANEDGAT1
SCHEMBL28061441 0.81 HDAC6 (0.36) HDAC6HDAC1HDAC2ELANEDGAT1
SCHEMBL29004075 0.81 RECQL (0.36) DGAT1CA12CA2CA14
SCHEMBL44143 0.80
SCHEMBL6116105 0.80
SCHEMBL27544433 0.79 CYP1A2 (0.47) HDAC6HDAC1HDAC2ELANELMNA
SCHEMBL3695618 0.78 TSHR (0.36) HDAC6HDAC1HDAC2ELANEDGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 508 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119707872-A Method for amidation of carboxylic acid and continuous flow photochemistry device 国网安徽省电力有限公司电力科学研究院 2025-03-28 CN claimed
CN-119504652-A Method for amidating carboxylic acid and gas-liquid mixed flow photochemical device 国网安徽省电力有限公司电力科学研究院 2025-02-25 CN claimed
CN-119504653-A Carboxylic acid amidation method 国网安徽省电力有限公司电力科学研究院 2025-02-25 CN claimed
CN-119144015-A Preparation method of antibacterial mimetic peptide hydrogel 淮阴工学院 2024-12-17 CN claimed
CN-119143934-A Preparation method of temperature-sensitive antibacterial mimetic peptide hydrogel 淮阴工学院 2024-12-17 CN claimed
CN-118580856-A SUMO-C3H8BrN probe, synthesis method and application 大连理工大学 2024-09-03 CN claimed
EP-3908571-A1 KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF XWPharma Ltd. (KY) 2021-11-17 EP claimed
WO-2020143198-A1 KETAMINE DERIVATIVES AND COMPOSITIONS THEREOF XW LABORATORIES INC. (KY) 2020-07-16 WO claimed
CN-107207562-B Prodrugs of 17 β -HSD1 inhibitors 佛恩多制药有限公司 2020-03-06 CN claimed
CN-109897048-A 10-Methoxycamptothecine glycinate, preparation method and purposes 哈尔滨理工大学 2019-06-18 CN claimed
CN-107207562-A Prodrugs of 17 beta-HSD 1 inhibitors 佛恩多制药有限公司 2017-09-26 CN claimed
CN-105968170-A Fluorescent probe substrate of dipeptidyl peptidase IV as well as preparation method and application of fluorescent probe substrate 安阳师范学院 2016-09-28 CN claimed
CN-102935066-B Irinotecan liposome preparation and preparation method thereof QILU PHARMACEUTICAL CO LTD 2014-09-17 CN claimed
CN-102935066-A Irinotecan liposome preparation and preparation method thereof QILU PHARMACEUTICAL CO LTD 2013-02-20 CN claimed
CN-102649810-A Camptothecin derivative and preparation method and application thereof UNIV NORTHEAST FORESTRY 2012-08-29 CN claimed
EP-2172508-B1 Process for preparing branched polyamines and formulations thereof for use in medical applications TYCO HEALTHCARE (US) 2012-03-28 EP claimed
US-20100087668-A1 Branched Polyamines And Formulations Thereof For Use In Medical Devices TYCO HEALTHCARE GROUP LP 2010-04-08 US claimed
EP-2172508-A1 Branched polyamines and formulations thereof for use in medical devices Tyco Healthcare Group LP (US) 2010-04-07 EP claimed
CN-1303086-C Compound of dual functional esterified prodrug of Cefetamet, and oral preparation ZHU XIAOMAO (CN) 2007-03-07 CN claimed
CN-1687076-A Compound of dual functional esterified prodrug of Cefetamet, and oral preparation ZHU XIAOMAO (CN) 2005-10-26 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100087668-A1 Branched Polyamines And Formulations Thereof For Use In Medical Devices SRM, PNMT, PARG HDAC6 1272/4885HDAC1 2099/4885HDAC2 1228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.