⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11474731 | 0.69 | — | — | |
| SCHEMBL10029554 | 0.67 | — | — | |
| SCHEMBL19604174 | 0.67 | — | — | |
| SCHEMBL19589354 | 0.64 | SMPD3 (0.30) | — | |
| SCHEMBL20077039 | 0.61 | — | — | |
| SCHEMBL5321218 | 0.61 | ALDH1A1 (0.33) | — | |
| SCHEMBL20077380 | 0.58 | TRPA1 (0.33) | — | |
| SCHEMBL9479124 | 0.55 | — | — | |
| SCHEMBL24950422 | 0.53 | — | — | |
| SCHEMBL14446884 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200353076-A1 | ANTI-FOLATE RECEPTOR ALPHA ANTIBODY CONJUGATES AND THEIR USES | SUTRO BIOPHARMA, INC. | 2020-11-12 | — | — | US | disclosed |
| US-9732161-B2 | Modified Fc proteins comprising site-specific non-natural amino acid residues, conjugates of the same, methods of their preparation and methods of their use | SUTRO BIOPHARMA, INC. (US) | 2017-08-15 | — | — | US | disclosed |