Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 19/20 | 0.39 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | LOX | P28300 | 2/20 | 0.37 |
| ▸ | LOXL3 | P58215 | 2/20 | 0.37 |
| ▸ | LOXL1 | Q08397 | 2/20 | 0.37 |
| ▸ | LOXL4 | Q96JB6 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19255571 | 0.84 | LOXL2 (0.37) | LOXL2DAOAOC3LOXLOXL3 | |
| SCHEMBL19255847 | 0.82 | LOXL2 (0.40) | LOXL2DAOAOC3LOXLOXL3 | |
| SCHEMBL19255708 | 0.78 | LOXL2 (0.52) | LOXL2DAOAOC3 | |
| SCHEMBL19255163 | 0.75 | LOXL2 (0.54) | LOXL2LOXLOXL3LOXL1LOXL4 | |
| SCHEMBL19255574 | 0.74 | LOXL2 (0.51) | LOXL2DAOAOC3 | |
| SCHEMBL19255398 | 0.74 | LOXL2 (0.38) | LOXL2DAOAOC3LOXLOXL3 | |
| SCHEMBL19255048 | 0.74 | LOXL2 (0.42) | LOXL2DAOAOC3LOXLOXL3 | |
| SCHEMBL19255244 | 0.73 | LOXL2 (0.63) | LOXL2DAOAOC3LOXLOXL3 | |
| Hydrochloric Acid SCHEMBL20699531 | 0.72 | LOXL2 (0.64) | LOXL2DAOAOC3LOXLOXL3 | |
| SCHEMBL20699486 | 0.72 | LOXL2 (0.59) | LOXL2DAOAOC3LOXLOXL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136870-A9 | HALOALLYLAMINE INDOLE AND AZAINDOLE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2018-02-15 | — | — | WO | disclosed |
| WO-2017136870-A1 | HALOALLYLAMINE INDOLE AND AZAINDOLE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2017-08-17 | — | — | WO | disclosed |