Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 2/20 | 0.49 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.47 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.47 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.47 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14306795 | 1.00 | PYGB (0.49) | PYGBLGALS3LGALS1LGALS9LGALS8 | |
| SCHEMBL13768389 | 1.00 | PYGB (0.49) | PYGBLGALS3LGALS1LGALS9LGALS8 | |
| SCHEMBL26210669 | 1.00 | PYGB (0.49) | PYGBLGALS3LGALS1LGALS9LGALS8 | |
| SCHEMBL5019779 | 0.98 | PYGB (0.46) | PYGBLGALS3LGALS1LGALS9LGALS8 | |
| SCHEMBL20692159 | 0.98 | PYGB (0.46) | PYGBLGALS3LGALS1LGALS9LGALS8 | |
| SCHEMBL15343514 | 0.98 | PYGB (0.46) | PYGBLGALS3LGALS1LGALS9LGALS8 | |
| SCHEMBL14465071 | 0.98 | PYGB (0.46) | PYGBLGALS3LGALS1LGALS9LGALS8 | |
| SCHEMBL14274191 | 0.98 | PYGB (0.46) | PYGBLGALS3LGALS1LGALS9LGALS8 | |
| SCHEMBL22652623 | 0.91 | FBP1 (0.46) | PYGBLGALS3LGALS1LGALS9LGALS8 | |
| SCHEMBL18081360 | 0.91 | FBP1 (0.46) | PYGBLGALS3LGALS1LGALS9LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136739-A1 | GLUCOSE CONJUGATES OF TRIPTOLIDE, ANALOGS AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-08-10 | — | — | WO | disclosed |