Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | TPO | P07202 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19250615 | 0.78 | HCAR2 (0.34) | — | |
| SCHEMBL19255585 | 0.77 | REN (0.34) | — | |
| SCHEMBL19886409 | 0.69 | ADORA1 (0.49) | — | |
| SCHEMBL3664672 | 0.61 | TSHR (0.42) | MPOTPOCYP3A4 | |
| SCHEMBL2525288 | 0.58 | DHODH (0.45) | — | |
| SCHEMBL16637217 | 0.57 | TSHR (0.46) | MPOTPOCYP3A4 | |
| SCHEMBL3434650 | 0.57 | GHSR (0.42) | CYP3A4 | |
| SCHEMBL1066576 | 0.55 | TSHR (0.67) | — | |
| Hydrochloric Acid SCHEMBL10534368 | 0.55 | TSHR (0.41) | KDM1A | |
| SCHEMBL1252285 | 0.55 | PARP1 (0.71) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133670-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |