SCHEMBL19255750

SCHEMBL19255750

C=N/C=C\c1c(C)sc2ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.38
CYP1A2 P05177 2/20 0.35
CYP2D6 P10635 2/20 0.35
CYP1A1 P04798 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
HTR2A P28223 1/20 0.35
CYP2C19 P33261 1/20 0.35
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 3/20 0.35
LMNA P02545 1/20 0.35
CASP1 P29466 1/20 0.35
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34
TUBA3C P0DPH7 1/20 0.34
TUBA1B P68363 1/20 0.34
TUBA4A P68366 1/20 0.34
TUBB4B P68371 1/20 0.34
TUBB3 Q13509 1/20 0.34
TUBB2A Q13885 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21895264 0.79 GPR3 (0.43) GPR3CYP1A2CYP2D6CYP1A1CYP3A4
SCHEMBL19266766 0.78 GPR3 (0.39) GPR3CYP1A2CYP2D6CYP1A1CYP3A4
SCHEMBL20941925 0.77 GPR3 (0.44) GPR3CYP1A2CYP2D6CYP1A1CYP3A4
SCHEMBL19255748 0.77 TUBB4A (0.52) GPR3ALDH1A1KDM4ELMNACASP1
SCHEMBL14139942 0.75 GPR3 (0.39) GPR3CYP1A2CYP2D6CYP1A1CYP3A4
SCHEMBL19257688 0.73 KDM4E (0.38) GPR3CYP1A2CYP2D6CYP1A1CYP3A4
SCHEMBL1093585 0.73 GPR3 (0.44) GPR3CYP1A2CYP2D6CYP1A1CYP3A4
SCHEMBL25520959 0.71 GPR3 (0.35) GPR3CYP1A2CYP2D6CYP1A1CYP3A4
SCHEMBL22789097 0.69 GPR3 (0.44) GPR3CYP1A2CYP2D6CYP1A1CYP3A4
SCHEMBL25520949 0.69 LIMK1 (0.36) GPR3CYP1A2CYP2D6CYP1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9735373-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-08-15 US disclosed