Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 20/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 9/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 8/20 | 1.00 |
| ▸ | HSD11B2 | P80365 | 2/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1031723 | 1.00 | HSD11B1 (1.00) | HSD11B1CYP3A4CYP2D6HSD11B2CYP2C9 | |
| SCHEMBL1771114 | 1.00 | HSD11B1 (1.00) | HSD11B1CYP3A4CYP2D6HSD11B2CYP2C9 | |
| SCHEMBL1771113 | 1.00 | HSD11B1 (1.00) | HSD11B1CYP3A4CYP2D6HSD11B2CYP2C9 | |
| SCHEMBL1034031 | 1.00 | HSD11B1 (1.00) | HSD11B1CYP3A4CYP2D6HSD11B2CYP2C9 | |
| SCHEMBL1034029 | 1.00 | HSD11B1 (1.00) | HSD11B1CYP3A4CYP2D6HSD11B2CYP2C9 | |
| SCHEMBL12596538 | 1.00 | HSD11B1 (1.00) | HSD11B1CYP3A4CYP2D6HSD11B2CYP2C9 | |
| SCHEMBL1031724 | 1.00 | HSD11B1 (1.00) | HSD11B1CYP3A4CYP2D6HSD11B2CYP2C9 | |
| SCHEMBL12596596 | 1.00 | HSD11B1 (1.00) | HSD11B1CYP3A4CYP2D6HSD11B2CYP2C9 | |
| SCHEMBL1033422 | 0.95 | HSD11B1 (0.91) | HSD11B1CYP3A4CYP2D6HSD11B2CYP2C9 | |
| SCHEMBL12649020 | 0.95 | HSD11B1 (0.91) | HSD11B1CYP3A4CYP2D6HSD11B2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10039772-B2 | Methods and compositions for treating alcohol use disorders | SANNA PIETRO PAOLO (US) | 2018-08-07 | — | — | US | disclosed |
| US-20170232007-A1 | METHODS AND COMPOSITIONS FOR TREATING ALCOHOL USE DISORDERS | SANNA PIETRO PAOLO (US) | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10039772-B2 | Methods and compositions for treating alcohol use disorders | HSD3B1, HSD11B1, HSD3B2 | HSD11B1 2/4885CYP3A4 133/4885CYP2D6 193/4885 |
| US-20170232007-A1 | METHODS AND COMPOSITIONS FOR TREATING ALCOHOL USE DISORDERS | HSD3B1, HSD11B1, HSD3B2 | HSD11B1 2/4885CYP3A4 133/4885CYP2D6 193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.