Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL346851 | 1.00 | CRBN (0.41) | CRBNKDM4ELMNACYP2C19SMN1; SMN2 | |
| SCHEMBL529832 | 0.97 | CRBN (0.43) | CRBNKDM4ELMNACYP2C19SMN1; SMN2 | |
| SCHEMBL9238801 | 0.94 | CRBN (0.41) | CRBNKDM4ELMNACYP2C19SMN1; SMN2 | |
| SCHEMBL19585725 | 0.85 | CRBN (0.44) | CRBNKDM4ELMNACYP2C19ALDH1A1 | |
| SCHEMBL22271225 | 0.82 | CRBN (0.48) | CRBNKDM4ELMNACYP2C19 | |
| SCHEMBL20633686 | 0.79 | NEK2 (0.36) | CRBNKDM4ELMNACYP2C19ALDH1A1 | |
| SCHEMBL6229229 | 0.77 | OPRM1 (0.46) | CRBNSMN1; SMN2 | |
| SCHEMBL483007 | 0.77 | OPRM1 (0.46) | CRBNSMN1; SMN2 | |
| SCHEMBL428337 | 0.77 | ESR2 (0.38) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL2527186 | 0.76 | NEK2 (0.41) | CRBNKDM4ELMNACYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170233529-A1 | BIS(AZOBENZENE) DIAMINES AND PHOTOMECHANICAL POLYMERS MADE THEREFROM | GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2017-08-17 | — | — | US | disclosed |