Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483007 | 1.00 | OPRM1 (0.46) | OPRM1OPRL1SMN1; SMN2CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL4339042 | 0.98 | OPRM1 (0.45) | OPRM1OPRL1SMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL2522078 | 0.98 | OPRM1 (0.47) | OPRM1OPRL1SMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL4956385 | 0.93 | OPRM1 (0.49) | OPRM1OPRL1SMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL17925986 | 0.93 | — | — | |
| SCHEMBL16190003 | 0.87 | — | — | |
| SCHEMBL4289914 | 0.82 | SMN1; SMN2 (0.50) | OPRM1OPRL1SMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL20941858 | 0.81 | OPRM1 (0.41) | OPRM1OPRL1SMN1; SMN2CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL17101303 | 0.80 | OPRM1 (0.40) | OPRM1OPRL1SMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL2106280 | 0.79 | OPRM1 (0.45) | OPRM1OPRL1SMN1; SMN2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237903-B1 | METHODS FOR AUTHENTICATION AND IDENTIFICATION OF PETROLEUM PRODUCTS | EXXONMOBIL RES & ENG CO (US) | 2020-02-26 | — | — | EP | claimed |
| EP-3237904-A1 | METHODS FOR DETERMINING CONDITION AND QUALITY OF PETROLEUM PRODUCTS | Exxonmobil Research And Engineering Company (US) | 2017-11-01 | — | — | EP | claimed |
| EP-3237903-A1 | METHODS FOR AUTHENTICATION AND IDENTIFICATION OF PETROLEUM PRODUCTS | Exxonmobil Research And Engineering Company (US) | 2017-11-01 | — | — | EP | claimed |
| WO-2016106214-A1 | METHODS FOR DETERMINING CONDITION AND QUALITY OF PETROLEUM PRODUCTS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2016-06-30 | — | — | WO | claimed |
| US-20160187315-A1 | METHODS FOR DETERMINING CONDITION AND QUALITY OF PETROLEUM PRODUCTS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2016-06-30 | — | — | US | claimed |
| US-20160187314-A1 | METHODS FOR AUTHENTICATION AND IDENTIFICATION OF PETROLEUM PRODUCTS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2016-06-30 | — | — | US | claimed |
| WO-2016106211-A1 | METHODS FOR AUTHENTICATION AND IDENTIFICATION OF PETROLEUM PRODUCTS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2016-06-30 | — | — | WO | claimed |
| EP-3237903-B1 | METHODS FOR AUTHENTICATION AND IDENTIFICATION OF PETROLEUM PRODUCTS | EXXONMOBIL RES & ENG CO (US) | 2020-02-26 | — | — | EP | disclosed |
| EP-3237904-A1 | METHODS FOR DETERMINING CONDITION AND QUALITY OF PETROLEUM PRODUCTS | Exxonmobil Research And Engineering Company (US) | 2017-11-01 | — | — | EP | disclosed |
| EP-3237903-A1 | METHODS FOR AUTHENTICATION AND IDENTIFICATION OF PETROLEUM PRODUCTS | Exxonmobil Research And Engineering Company (US) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016106211-A1 | METHODS FOR AUTHENTICATION AND IDENTIFICATION OF PETROLEUM PRODUCTS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2016-06-30 | — | — | WO | disclosed |
| US-20160187315-A1 | METHODS FOR DETERMINING CONDITION AND QUALITY OF PETROLEUM PRODUCTS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2016-06-30 | — | — | US | disclosed |
| WO-2016106214-A1 | METHODS FOR DETERMINING CONDITION AND QUALITY OF PETROLEUM PRODUCTS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2016-06-30 | — | — | WO | disclosed |
| US-20160187314-A1 | METHODS FOR AUTHENTICATION AND IDENTIFICATION OF PETROLEUM PRODUCTS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2016-06-30 | — | — | US | disclosed |
| US-20050288351-A1 | Azaspiro compounds for the treatment of pain | SCHWARZ PHARMA AG (DE) | 2005-12-29 | — | — | US | disclosed |
| EP-1485352-B1 | AZASPIRO COMPOUNDS FOR THE TREATMENT OF PAIN | SANOL ARZNEI SCHWARZ GMBH (DE) | 2005-06-29 | — | — | EP | disclosed |
| EP-1520854-A2 | Aza-Spirocompounds for the treatment of pain | SCHWARZ PHARMA AG (DE) | 2005-04-06 | — | — | EP | disclosed |
| EP-1485352-A1 | AZASPIRO COMPOUNDS FOR THE TREATMENT OF PAIN | SCHWARZ PHARMA AG (DE) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003074486-A1 | AZASPIRO COMPOUNDS FOR THE TREATMENT OF PAIN | SCHWARZ PHARMA AG (DE) | 2003-09-12 | — | — | WO | disclosed |
| US-4228179-A | ANTICONVULSANTS | WARNER-LAMBERT COMPANY (US) | 1980-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288351-A1 | Azaspiro compounds for the treatment of pain | TPMT, P2RY13, OPRL1 | OPRM1 32/4885OPRL1 3/4885SMN1; SMN2 1807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.