Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12120674 | 0.81 | MMP8 (0.53) | MMP8PKMKDM4ECYP4F2CYP4A11 | |
| SCHEMBL4426319 | 0.79 | MMP8 (0.76) | MMP8PKMKDM4ECYP4F2CYP4A11 | |
| SCHEMBL7857447 | 0.79 | MMP8 (0.59) | MMP8PKMKDM4ECYP4F2CYP4A11 | |
| SCHEMBL1785998 | 0.78 | ALDH1A1 (0.50) | MMP8PKMKDM4ECYP4F2CYP4A11 | |
| SCHEMBL12574780 | 0.78 | MMP8 (0.58) | MMP8PKMKDM4ECYP4F2CYP4A11 | |
| SCHEMBL12549769 | 0.77 | MMP8 (0.53) | MMP8PKMKDM4ECYP4F2CYP4A11 | |
| SCHEMBL234014 | 0.77 | MMP8 (0.56) | MMP8PKMKDM4ECYP4F2CYP4A11 | |
| SCHEMBL18388352 | 0.77 | MMP8 (0.39) | MMP8 | |
| SCHEMBL996813 | 0.76 | MMP8 (0.71) | MMP8PKMKDM4ECYP4F2CYP4A11 | |
| SCHEMBL17617148 | 0.76 | MMP8 (0.56) | MMP8PKMKDM4ECYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521711-B1 | QUATERNARY AMMONIUM SALT PRODRUGS | ALKERMES PHARMA IRELAND LTD (IE) | 2017-08-16 | — | — | EP | disclosed |