Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 6/20 | 0.42 |
| ▸ | CA1 | P00915 | 6/20 | 0.42 |
| ▸ | CA2 | P00918 | 6/20 | 0.42 |
| ▸ | CA9 | Q16790 | 6/20 | 0.42 |
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13270350 | 0.88 | TDP1 (0.42) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL1925644 | 0.87 | CA1 (0.42) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL13270349 | 0.81 | CA12 (0.36) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL1926878 | 0.81 | CA12 (0.38) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL9601113 | 0.81 | TDP1 (0.47) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL1948943 | 0.80 | CA12 (0.35) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL5493650 | 0.78 | TDP1 (0.59) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL19931568 | 0.78 | ALDH1A1 (0.44) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL29422137 | 0.76 | CA12 (0.41) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL1927057 | 0.76 | CA2 (0.35) | TDP1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509941-A2 | N-ACYLATED HYDROXYLAMINE DERIVATIVES AND O-ACYLATED HYDROXYLAMINE DERIVATIVES | The Johns Hopkins University (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011071951-A2 | N-ACYLOXYSULFONAMIDE AND N-HYDROXY-N-ACYLSULFONAMIDE DERIVATIVES | JOHNS HOPKINS UNIVERSITY (US) | 2011-06-16 | — | — | WO | disclosed |