Sugi Predict

Sugi Predict / Compounds / SCHEMBL1925658

SCHEMBL1925658

SCHEMBL1925658

CC1(c2c[nH]c3ccccc23)NC(=O)NC1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 5/20 0.50
▸ MGAM O43451 4/20 0.50
▸ SI P14410 4/20 0.50
▸ MGAM2 Q2M2H8 4/20 0.50
▸ HTR1A P08908 1/20 0.44
▸ HTR2A P28223 1/20 0.44
▸ HTR7 P34969 1/20 0.44
▸ HTR6 P50406 1/20 0.44
▸ TP53 P04637 1/20 0.43
▸ PIM1 P11309 2/20 0.42
▸ PRKD3 O94806 1/20 0.41
▸ CCNB2 O95067 1/20 0.41
▸ CCNE2 O96020 1/20 0.41
▸ ABL1 P00519 1/20 0.41
▸ PRKCG P05129 1/20 0.41
▸ PRKCB P05771 1/20 0.41
▸ CDK1 P06493 1/20 0.41
▸ CDK4 P11802 1/20 0.41
▸ CCNB1 P14635 1/20 0.41
▸ PRKCA P17252 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11634983 0.76 CYP2C9 (0.60) GAAMGAMSIMGAM2HTR1A
SCHEMBL29074193 0.75 GAA (0.50) GAAMGAMSIMGAM2HTR1A
SCHEMBL542713 0.74 PTGER3 (0.49) HTR7MAPTPTGER3TNKS
SCHEMBL17622901 0.74 PIM1 (0.60) GAAMGAMSIMGAM2HTR1A
SCHEMBL13043371 0.73 SIRT2 (0.43) GAAMGAMSIMGAM2TP53
SCHEMBL11665388 0.72 KMT2A (0.47) HTR1AHTR2AHTR7HTR6ALDH1A1
SCHEMBL9402447 0.71 MAPT (0.41) PIM1ALDH1A1MAPTPTGER3TNKS
SCHEMBL12502546 0.70 PTGER3 (0.45) HTR2AALDH1A1MAPTPTGER3TNKS
SCHEMBL10736336 0.70 TSHR (0.46) PTGER3
SCHEMBL15535570 0.70 AKR1B1 (0.49) HTR2AALDH1A1MAPTPTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582454-B2 5-substituted hydantoin racemase, DNA coding for the racemase, and processes for producing optically active amino acids AJINOMOTO CO. INC. (JP) 2009-09-01 — — US claimed
US-20060246553-A1 5-substituted hydantoin racemase, DNA coding for the racemase, and processes for producing optically active amino acids AJINOMOTO CO., INC. (JP) 2006-11-02 — — US claimed
US-7112431-B2 5-substituted hydantoin racemase, DNA coding for the racemase, and processes for producing optically active amino acids AJINOMOTO CO. INC. (JP) 2006-09-26 — — US claimed
US-20050084946-A1 5-substituted hydantoin racemase, DNA coding for the racemase, and processes for producing optically active amino acids AJINOMOTO CO., INC. (JP) 2005-04-21 — — US claimed
US-20020102713-A1 5-substituted hydantoin racemase, DNA coding for the racemase, and processes for producing optically active amino acids AJINOMOTO CO., INC. (JP) 2002-08-01 — — US claimed
CN-115772513-B D-carbamyl hydrolase mutant, gene, expression vector and application thereof 江南大学 2025-05-02 — — CN disclosed
CN-115772513-B D-carbamyl hydrolase mutant, gene, expression vector and application thereof 江南大学 2025-05-02 — — CN disclosed
CN-114686464-B Application of D-N-carbamyl hydrolase in production of D-tryptophan 湖南引航生物科技有限公司 2023-11-28 — — CN disclosed
WO-2016044777-A1 HAT INHIBITORS AND METHODS FOR THEIR USE ABBVIE INC. (US) 2016-03-24 — — WO disclosed
WO-2016044777-A1 HAT INHIBITORS AND METHODS FOR THEIR USE ABBVIE INC. (US) 2016-03-24 — — WO disclosed
EP-1188826-B1 5-substituted hydantoin racemase, DNA coding for the same, and process for producing optically active amino acids AJINOMOTO KK (JP) 2011-06-08 — — EP disclosed
US-7582454-B2 5-substituted hydantoin racemase, DNA coding for the racemase, and processes for producing optically active amino acids AJINOMOTO CO. INC. (JP) 2009-09-01 — — US disclosed
US-20060246553-A1 5-substituted hydantoin racemase, DNA coding for the racemase, and processes for producing optically active amino acids AJINOMOTO CO., INC. (JP) 2006-11-02 — — US disclosed
US-7112431-B2 5-substituted hydantoin racemase, DNA coding for the racemase, and processes for producing optically active amino acids AJINOMOTO CO. INC. (JP) 2006-09-26 — — US disclosed
US-20050084946-A1 5-substituted hydantoin racemase, DNA coding for the racemase, and processes for producing optically active amino acids AJINOMOTO CO., INC. (JP) 2005-04-21 — — US disclosed
US-6815195-B2 NUCLEOTIDE SEQUENCES CODING PREFERENTIAL PROTEIN FOR USE IN GENERATING RACEMIC AMINO ACIDS AJINOMOTO CO. INC. (JP) 2004-11-09 — — US disclosed
US-20020102713-A1 5-substituted hydantoin racemase, DNA coding for the racemase, and processes for producing optically active amino acids AJINOMOTO CO., INC. (JP) 2002-08-01 — — US disclosed
EP-1188826-A2 5-substituted hydantoin racemase, DNA coding for the same, and process for producing optically active amino acids Ajinomoto Co., Inc. (JP) 2002-03-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050084946-A1 5-substituted hydantoin racemase, DNA coding for the racemase, and processes for producing optically active amino acids HDHD5, HAAO, MTAP GAA 1303/4885MGAM 244/4885SI 647/4885
US-20020102713-A1 5-substituted hydantoin racemase, DNA coding for the racemase, and processes for producing optically active amino acids HDHD5, HAAO, MTAP GAA 1303/4885MGAM 244/4885SI 647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.