Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | DUT | P33316 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1926193 | 0.87 | ITGAV (0.37) | POLBNPSR1KDM4ELMNAHSD11B1 | |
| SCHEMBL28496305 | 0.73 | LMNA (0.41) | POLBKDM4ELMNAALDH1A1 | |
| SCHEMBL1925782 | 0.73 | MALT1 (0.41) | POLBLMNA | |
| SCHEMBL14675988 | 0.72 | POLB (0.48) | POLBRECQLDUTMMP1MMP2 | |
| SCHEMBL20538699 | 0.70 | POLB (0.46) | POLBRECQLDUTMMP1MMP2 | |
| SCHEMBL14675645 | 0.69 | POLB (0.45) | POLBBRD4RECQLDUTKDM4E | |
| SCHEMBL1926557 | 0.68 | TP53 (0.44) | POLBBRD4RECQLKDM4ELMNA | |
| SCHEMBL11610029 | 0.68 | LMNA (0.46) | POLBKDM4ELMNAALDH1A1 | |
| SCHEMBL264098 | 0.67 | CA1 (0.52) | POLBRECQLDUTKDM4ELMNA | |
| SCHEMBL30565211 | 0.67 | CA1 (0.52) | POLBRECQLDUTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011071951-A2 | N-ACYLOXYSULFONAMIDE AND N-HYDROXY-N-ACYLSULFONAMIDE DERIVATIVES | JOHNS HOPKINS UNIVERSITY (US) | 2011-06-16 | — | — | WO | disclosed |