Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9603154 | 0.85 | ELANE (0.46) | LMNAELANETP53ALDH1A1CYP2D6 | |
| SCHEMBL11611823 | 0.85 | ELANE (0.42) | LMNAELANECA12CA9TP53 | |
| SCHEMBL5706500 | 0.80 | CA12 (0.47) | LMNACA12CA9CA1CA2 | |
| SCHEMBL11773645 | 0.77 | ALDH1A1 (0.53) | TP53ALDH1A1CYP2D6POLBKDM4E | |
| SCHEMBL1925782 | 0.73 | MALT1 (0.41) | LMNATP53POLB | |
| SCHEMBL28496305 | 0.73 | LMNA (0.41) | LMNAELANESCN2ATP53ALDH1A1 | |
| SCHEMBL28648868 | 0.72 | LMNA (0.58) | LMNATP53ALDH1A1CYP2D6POLB | |
| SCHEMBL19852093 | 0.72 | LMNA (0.43) | LMNAELANECA12CA9TP53 | |
| SCHEMBL9944717 | 0.71 | CASP3 (0.43) | LMNACA12CA9ALDH1A1POLB | |
| SCHEMBL21424558 | 0.71 | CA12 (0.43) | LMNACA12CA9ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125727-A | Method of preparing imidazoisoindolediones | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |
| US-4062671-A | Imidazoisoindolediones, and the use thereof as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1977-12-13 | — | — | US | disclosed |
| US-4017510-A | ENANTIOMORPHS | AMERICAN CYANAMID COMPANY (US) | 1977-04-12 | — | — | US | disclosed |