Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.83 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.79 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL19209319 | 0.98 | GAA (0.80) | GAAL3MBTL1ITGB3ITGA2BMAOB | |
| SCHEMBL8488482 | 0.98 | L3MBTL1 (0.82) | GAAL3MBTL1ITGB3ITGA2BMAOB | |
| SCHEMBL7738999 | 0.95 | GAA (0.75) | GAAL3MBTL1ITGB3ITGA2BMAOB | |
| SCHEMBL26241763 | 0.93 | L3MBTL1 (0.79) | GAAL3MBTL1MAOBMAPTALDH1A1 | |
| SCHEMBL18868405 | 0.89 | L3MBTL1 (1.00) | GAAL3MBTL1MAOBMAPTALDH1A1 | |
| SCHEMBL757971 | 0.87 | L3MBTL1 (0.75) | GAAL3MBTL1MAOBMAPTALDH1A1 | |
| SCHEMBL24935612 | 0.84 | GAA (0.86) | GAAL3MBTL1MAOBMAPTALDH1A1 | |
| SCHEMBL10497781 | 0.84 | GAA (0.86) | GAAL3MBTL1TP53TSHRPLA2G4B | |
| SCHEMBL2039230 | 0.84 | GAA (0.86) | GAAL3MBTL1TP53TSHRPLA2G4B | |
| SCHEMBL10499017 | 0.84 | GAA (0.86) | GAAL3MBTL1TP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134547-A1 | TUBULYSIN ANALOGS AND METHODS FOR THEIR PREPARATION | PFIZER INC. (US) | 2017-08-10 | — | — | WO | disclosed |