Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.82 |
| ▸ | GAA | P10253 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19257733 | 0.98 | GAA (0.83) | L3MBTL1GAAMAPTALDH1A1MAOB | |
| Hydrochloric Acid SCHEMBL19209319 | 0.97 | GAA (0.80) | L3MBTL1GAAMAPTALDH1A1MAOB | |
| SCHEMBL26241763 | 0.95 | L3MBTL1 (0.79) | L3MBTL1GAAMAPTALDH1A1MAOB | |
| SCHEMBL7738999 | 0.94 | GAA (0.75) | L3MBTL1GAAMAPTALDH1A1MAOB | |
| SCHEMBL18868405 | 0.91 | L3MBTL1 (1.00) | L3MBTL1GAAMAPTALDH1A1MAOB | |
| SCHEMBL757971 | 0.89 | L3MBTL1 (0.75) | L3MBTL1GAAMAPTALDH1A1MAOB | |
| SCHEMBL834525 | 0.85 | L3MBTL1 (0.88) | L3MBTL1GAAMAPTALDH1A1MAOB | |
| SCHEMBL24396458 | 0.84 | L3MBTL1 (0.85) | L3MBTL1GAAMAPTALDH1A1MAOB | |
| SCHEMBL1470028 | 0.84 | L3MBTL1 (0.85) | L3MBTL1GAAMAPTALDH1A1TP53 | |
| SCHEMBL7609908 | 0.84 | L3MBTL1 (0.85) | L3MBTL1GAAMAPTALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877196-A | N- 4-(imidazolyl or pyrazolyl)phenyl(oxy, sulfinyl, sulfenyl or sulfonyl)alkyl!carboxamides, sulfonamides or phosphoramides having antiarrhythmic properties | AMERICAN CYANAMID COMPANY (US) | 1999-03-02 | — | — | US | disclosed |
| EP-0792873-A1 | N-(Phenoxyalkyl) carboxamides and their use as antiarrhythmic agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | disclosed |