Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 9/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | EGLN3 | Q9H6Z9 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6846943 | 0.90 | SLC9A1 (0.69) | SLC9A1RAB9AMAPTNPC1GLA | |
| SCHEMBL19257747 | 0.83 | SLC9A1 (0.62) | SLC9A1RAB9AMAPTNPC1GLA | |
| SCHEMBL4083657 | 0.82 | SLC9A1 (0.65) | SLC9A1RAB9AMAPTNPC1GLA | |
| SCHEMBL22267861 | 0.82 | SLC9A1 (0.61) | SLC9A1RAB9AMAPTNPC1GLA | |
| SCHEMBL5859945 | 0.80 | SLC9A1 (0.48) | SLC9A1TSHRGRM2KMT2ALMNA | |
| SCHEMBL283896 | 0.80 | SLC9A1 (1.00) | SLC9A1RAB9AMAPTNPC1GLA | |
| SCHEMBL13348076 | 0.80 | RAB9A (0.59) | SLC9A1RAB9AMAPTNPC1GLA | |
| SCHEMBL14796568 | 0.80 | SLC9A1 (0.79) | SLC9A1RAB9AMAPTNPC1GLA | |
| SCHEMBL1834794 | 0.77 | SLC9A1 (1.00) | SLC9A1RAB9AMAPTNPC1GLA | |
| SCHEMBL5637028 | 0.77 | SLC9A1 (0.80) | SLC9A1RAB9AMAPTNPC1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134547-A1 | TUBULYSIN ANALOGS AND METHODS FOR THEIR PREPARATION | PFIZER INC. (US) | 2017-08-10 | — | — | WO | disclosed |