Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.43 |
| ▸ | ITK | Q08881 | 2/20 | 0.36 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | PDE9A | O76083 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19258218 | 0.84 | ITK (0.37) | SCN9AITKKCNH2ROCK1MAOA | |
| SCHEMBL26064460 | 0.83 | RAB9A (0.39) | ITKKMT2AKCNH2ROCK1CCR3 | |
| SCHEMBL24795655 | 0.81 | ITK (0.35) | SCN9AITKMEN1KMT2AKCNH2 | |
| SCHEMBL19258243 | 0.78 | SCN9A (0.46) | SCN9AKCNH2ROCK1 | |
| SCHEMBL26715104 | 0.76 | CCR3 (0.34) | ITKKMT2AROCK1CCR3HTR6 | |
| SCHEMBL25443788 | 0.75 | BACE1 (0.32) | CDK1CCNB1CCNA2CDK2MEN1 | |
| SCHEMBL19257826 | 0.75 | SCN9A (0.43) | SCN9AKCNH2ROCK1 | |
| SCHEMBL24795327 | 0.74 | ITK (0.32) | ITKMEN1KMT2AROCK1 | |
| SCHEMBL19257824 | 0.74 | SCN9A (0.43) | SCN9AROCK1 | |
| SCHEMBL26411128 | 0.73 | SCN9A (0.33) | SCN9AITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3205658-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Universal Display Corporation (US) | 2017-08-16 | — | — | EP | disclosed |