Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 9/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 8/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19257828 | 0.83 | ROCK1 (0.34) | SCN9AROCK1 | |
| SCHEMBL19257824 | 0.82 | SCN9A (0.43) | SCN9AROCK1 | |
| SCHEMBL19258243 | 0.81 | SCN9A (0.46) | SCN9AROCK1ROCK2KCNH2 | |
| SCHEMBL19258028 | 0.81 | SIGMAR1 (0.37) | SCN9A | |
| SCHEMBL24790357 | 0.80 | ROCK1 (0.37) | SCN9AROCK1ROCK2KCNH2 | |
| SCHEMBL24146536 | 0.78 | MAPT (0.31) | SCN9AROCK1 | |
| SCHEMBL24790396 | 0.78 | ROCK1 (0.32) | SCN9AROCK1 | |
| SCHEMBL24790722 | 0.77 | SCN9A (0.31) | SCN9A | |
| SCHEMBL24790395 | 0.77 | ROCK1 (0.32) | ROCK1 | |
| SCHEMBL24790381 | 0.76 | ROCK1 (0.33) | ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3205658-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Universal Display Corporation (US) | 2017-08-16 | — | — | EP | disclosed |