Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 10/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 10/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 10/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.36 |
| ▸ | TSHR | P16473 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | USP2 | O75604 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19258222 | 0.86 | SIGMAR1 (0.42) | SIGMAR1PPARGPRKDCSCN9A | |
| SCHEMBL19258029 | 0.83 | IRAK4 (0.33) | PRKDCIRAK4 | |
| SCHEMBL19258220 | 0.82 | PRKDC (0.33) | PRKDCIRAK4SCN9A | |
| SCHEMBL19258027 | 0.82 | CLK4 (0.35) | SIGMAR1CLK4CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL17666808 | 0.81 | SIK2 (0.37) | CLK4MAPK1ADORA2APRKDCIRAK4 | |
| SCHEMBL19257826 | 0.81 | SCN9A (0.43) | SCN9A | |
| SCHEMBL26060446 | 0.79 | PDE2A (0.33) | HTR7MAPK14 | |
| SCHEMBL19258239 | 0.72 | ADORA2A (0.56) | SIGMAR1CLK4CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL19258252 | 0.71 | LMNA (0.41) | SIGMAR1CLK4CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL26060370 | 0.70 | HTR7 (0.33) | SIGMAR1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3205658-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Universal Display Corporation (US) | 2017-08-16 | — | — | EP | disclosed |