Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3360650 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2EPHX2SLC6A2HRH2DRD3 | |
| SCHEMBL3358972 | 0.81 | KDM1A (0.54) | SMN1; SMN2MAOBEPHX2SLC6A2HRH2 | |
| SCHEMBL3361513 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2EPHX2TACR1SLC6A2HRH2 | |
| SCHEMBL3359593 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2EPHX2TACR1SLC6A2HRH2 | |
| SCHEMBL3359980 | 0.81 | SLC6A2 (0.59) | SMN1; SMN2MAOBEPHX2SLC6A2HRH2 | |
| SCHEMBL3360273 | 0.81 | ALDH1A1 (0.59) | SMN1; SMN2MAOBTACR1ALDH1A1LMNA | |
| SCHEMBL13397148 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2EPHX2TACR1HRH2SLC6A3 | |
| SCHEMBL12875947 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2EPHX2TACR1HRH2SLC6A3 | |
| SCHEMBL3359767 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2EPHX2TACR1HRH2SLC6A3 | |
| SCHEMBL4105154 | 0.79 | EPHX2 (0.71) | SMN1; SMN2EPHX2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170233386-A1 | Compounds Which Have a Protective Activity with Respect to the Action of Toxins and of Viruses with an Intracellular Mode of Action | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233386-A1 | Compounds Which Have a Protective Activity with Respect to the Action of Toxins and of Viruses with an Intracellular Mode of Action | HAVCR2, MAVS, ANTXR2 | SMN1; SMN2 3088/4885ACHE 1186/4885BACE1 1327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.