Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19258033 | 0.82 | ABL1 (0.38) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL18814933 | 0.80 | S1PR1 (0.41) | NPC1CYP1A2CYP2C19CYP2D6CLK4 | |
| SCHEMBL25637284 | 0.79 | HTR2A (0.40) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL18729633 | 0.79 | PDCD1 (0.44) | NPC1CYP1A2CYP2C19CYP2D6CLK4 | |
| SCHEMBL3831411 | 0.78 | CASP3 (0.50) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL24756261 | 0.78 | ABL1 (0.41) | CASP3SENP7NPC1ABL1HTR2A | |
| SCHEMBL26355706 | 0.78 | ABL1 (0.38) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL807820 | 0.77 | NPC1 (0.62) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL17253659 | 0.76 | ABL1 (0.49) | ABL1CYP1A2HTR2AHTR2CHTR2B | |
| SCHEMBL19373370 | 0.76 | CYP1A2 (0.42) | NPC1CYP1A2CYP2C19CYP2D6CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3205658-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Universal Display Corporation (US) | 2017-08-16 | — | — | EP | disclosed |