SCHEMBL19258033

SCHEMBL19258033

Cc1cc(C)c(C)c(-c2cc3cc(CC(C)C)ccc3cn2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 2/20 0.38
S1PR1 P21453 1/20 0.34
S1PR3 Q99500 1/20 0.34
KDM4E B2RXH2 2/20 0.33
CASP3 P42574 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
NR3C1 P04150 1/20 0.31
PGR P06401 1/20 0.31
NR3C2 P08235 1/20 0.31
TACR1 P25103 2/20 0.31
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
HTR2B P41595 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19258030 0.82 CASP3 (0.43) ABL1S1PR1S1PR3KDM4ECASP3
SCHEMBL24756261 0.81 ABL1 (0.41) ABL1KDM4ECASP3SENP7GABRA1
SCHEMBL21577555 0.79 AR (0.37) ABL1S1PR1S1PR3KDM4EGABRA1
SCHEMBL25776462 0.76 NPC1 (0.51) KDM4ECASP3SENP8SENP7SENP6
SCHEMBL17253659 0.74 ABL1 (0.49) ABL1KDM4EGABRA1GABRB2HTR2A
SCHEMBL24795648 0.74 ABL1 (0.36) ABL1KDM4EPDE10ANPC1
SCHEMBL26783764 0.73 ROCK1 (0.36) ABL1KDM4EGABRA1GABRB2NOS3
SCHEMBL23426121 0.73 AKT1 (0.32) NOS3NOS1NOS2
SCHEMBL25518666 0.73 NR3C1 (0.33) KDM4EGABRA1GABRB2NR3C1PGR
SCHEMBL25637284 0.72 HTR2A (0.40) ABL1CASP3SENP8SENP7SENP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3205658-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2017-08-16 EP disclosed