Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 4/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.31 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | BRS3 | P32247 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.31 |
| ▸ | ITK | Q08881 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26060550 | 0.86 | PRKDC (0.38) | PRKDCSCN9AKCNH2STAT3CAMKK1 | |
| SCHEMBL19258217 | 0.84 | PRKDC (0.36) | PRKDCKCNH2CAMKK1CAMKK2JAK2 | |
| SCHEMBL19258254 | 0.83 | SIGMAR1 (0.43) | PRKDCSCN9ASTAT3SIGMAR1 | |
| SCHEMBL26064536 | 0.81 | FEN1 (0.31) | FEN1KCNH2 | |
| SCHEMBL19258220 | 0.78 | PRKDC (0.33) | PRKDCSCN9AEGFR | |
| SCHEMBL19143219 | 0.77 | PIM1 (0.38) | PRKDCSCN9AEGFRJAK2SIGMAR1 | |
| SCHEMBL24795164 | 0.77 | CAMKK1 (0.38) | PRKDCKCNH2CAMKK1CAMKK2JAK2 | |
| SCHEMBL26064511 | 0.77 | RPS6KB1 (0.41) | STAT3CAMKK1CAMKK2SIGMAR1 | |
| SCHEMBL19258223 | 0.77 | PRKDC (0.33) | PRKDCSCN9AEGFR | |
| SCHEMBL21204322 | 0.73 | ADORA2A (0.46) | EGFRJAK2CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3205658-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Universal Display Corporation (US) | 2017-08-16 | — | — | EP | disclosed |