Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934018 | 0.79 | TYR (0.48) | TYRNPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL13602061 | 0.70 | CCR1 (0.46) | TYRNPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL20621292 | 0.69 | CHRNA7 (0.33) | TYRLMNAALDH1A1CHRNA7 | |
| SCHEMBL2741630 | 0.69 | ESR1 (0.38) | TYRNPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL179333 | 0.69 | LMNA (0.50) | TYRNPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL15614472 | 0.68 | KRAS (0.34) | TYRNPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL14116462 | 0.68 | ESR1 (0.35) | TYRNPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL25393082 | 0.68 | DHFR (0.37) | NPC1LMNARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL25393080 | 0.68 | DHFR (0.37) | NPC1LMNARAB9ASMN1; SMN2KDM4E | |
| SCHEMBL15360260 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133657-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |