Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19207067 | 1.00 | APLNR (0.37) | APLNR | |
| SCHEMBL21192943 | 0.72 | GBA1 (0.38) | APLNR | |
| SCHEMBL19256482 | 0.72 | ALPL (0.30) | — | |
| SCHEMBL1584166 | 0.70 | — | — | |
| SCHEMBL1584163 | 0.70 | — | — | |
| SCHEMBL16771834 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL14911949 | 0.68 | APLNR (0.41) | APLNR | |
| Hydrochloric Acid SCHEMBL15775906 | 0.68 | APLNR (0.41) | APLNR | |
| Hydrochloric Acid SCHEMBL14911947 | 0.68 | APLNR (0.41) | APLNR | |
| SCHEMBL19207101 | 0.67 | GRM2 (0.32) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414241-B1 | HALO-SUBSTITUTED PIPERIDINES AS OREXIN RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2022-05-04 | — | — | EP | disclosed |
| WO-2017139603-A1 | HALO-SUBSTITUTED PIPERIDINES AS OREXIN RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2017-08-17 | — | — | WO | disclosed |