Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 8/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1638804 | 0.83 | CHEK1 (0.44) | RPS6KA5DAOKMT2AALDH1A1MEN1 | |
| SCHEMBL18442481 | 0.77 | DAO (0.38) | RPS6KA5DAOKDM4EMAPTKMT2A | |
| SCHEMBL29510696 | 0.77 | DAO (0.38) | RPS6KA5DAOKDM4EMAPTKMT2A | |
| SCHEMBL30308887 | 0.75 | POLB (0.42) | KDM4EMAPTALDH1A1 | |
| SCHEMBL19259003 | 0.72 | HDAC8 (0.38) | KDM4E | |
| SCHEMBL7844696 | 0.72 | RPS6KA5 (0.41) | RPS6KA5DAOKDM4EMAPTKMT2A | |
| SCHEMBL29557414 | 0.72 | RPS6KA5 (0.41) | RPS6KA5KDM4EMAPTKMT2AALDH1A1 | |
| SCHEMBL256344 | 0.72 | RPS6KA5 (0.41) | RPS6KA5KDM4EMAPTKMT2AALDH1A1 | |
| SCHEMBL19258999 | 0.72 | — | — | |
| Water SCHEMBL7479800 | 0.71 | RPS6KA5 (0.40) | RPS6KA5DAOKDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133657-A1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | disclosed |