Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENGASE | Q8NFI3 | 1/20 | 0.35 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.35 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.35 |
| ▸ | GJB2 | P29033 | 5/20 | 0.35 |
| ▸ | TYR | P14679 | 4/20 | 0.35 |
| ▸ | AMY2A | P04746 | 3/20 | 0.33 |
| ▸ | CD209 | Q9NNX6 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 2/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19248853 | 1.00 | ENGASE (0.35) | ENGASELGALS3LGALS8LGALS4GJB2 | |
| SCHEMBL17193641 | 1.00 | ENGASE (0.35) | ENGASELGALS3LGALS8LGALS4GJB2 | |
| SCHEMBL20733443 | 1.00 | ENGASE (0.35) | ENGASELGALS3LGALS8LGALS4GJB2 | |
| SCHEMBL19258981 | 1.00 | ENGASE (0.35) | ENGASELGALS3LGALS8LGALS4GJB2 | |
| SCHEMBL19935512 | 1.00 | ENGASE (0.35) | ENGASELGALS3LGALS8LGALS4GJB2 | |
| SCHEMBL20889746 | 1.00 | ENGASE (0.35) | ENGASELGALS3LGALS8LGALS4GJB2 | |
| SCHEMBL23709922 | 0.96 | FGF1 (0.35) | ENGASELGALS3LGALS8LGALS4GJB2 | |
| SCHEMBL14375103 | 0.94 | GJB2 (0.36) | ENGASELGALS3LGALS8LGALS4GJB2 | |
| SCHEMBL19350572 | 0.90 | ENGASE (0.36) | ENGASELGALS3LGALS8LGALS4GJB2 | |
| SCHEMBL26858411 | 0.89 | GJB2 (0.34) | GJB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10773011-B2 | Therapeutic compositions for viral-associated disease states and methods of making and using same | ImMutriX Therapeutics, Inc. (US) | 2020-09-15 | — | — | US | disclosed |
| US-20170232183-A1 | Therapeutic Compositions for Viral-Associated Disease States and Methods of Making and Using Same | ImMutriX Therapeutics, Inc. | 2017-08-17 | — | — | US | disclosed |