Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24066456 | 0.91 | USP2 (0.30) | — | |
| SCHEMBL1167764 | 0.82 | PTGS1 (0.43) | LMNASLC6A6CYP2C19BLMPTGS1 | |
| SCHEMBL7770123 | 0.79 | PTGS1 (0.41) | LMNASLC6A6CYP2C19BLMPTGS1 | |
| SCHEMBL7904192 | 0.79 | PTGS1 (0.41) | LMNASLC6A6CYP2C19BLMPTGS1 | |
| SCHEMBL226337 | 0.79 | PTGS1 (0.41) | LMNASLC6A6CYP2C19BLMPTGS1 | |
| SCHEMBL2889658 | 0.79 | PTGS1 (0.41) | LMNASLC6A6CYP2C19BLMPTGS1 | |
| SCHEMBL3219118 | 0.77 | LMNA (0.46) | LMNASLC6A6CYP2C19BLMPTGS1 | |
| SCHEMBL8748262 | 0.76 | CA1 (0.39) | LMNASLC6A6CYP2C19BLMPTGS1 | |
| SCHEMBL2321365 | 0.73 | PTGS1 (0.36) | LMNASLC6A6CYP2C19BLMPTGS1 | |
| SCHEMBL20553573 | 0.73 | APP (0.44) | LMNASLC6A6CYP2C19BLMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732105-B2 | Targeted nitroxide agents | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2017-08-15 | — | — | US | disclosed |