Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19208963 | 0.82 | DDB1 (0.53) | DDB1CRBNL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL19208947 | 0.82 | KMT2A (0.55) | DDB1CRBNL3MBTL1NPC1RAB9A | |
| SCHEMBL3654430 | 0.81 | DDB1 (0.52) | DDB1CRBNL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL16875197 | 0.81 | DDB1 (0.52) | DDB1CRBNL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL25787780 | 0.78 | DDB1 (0.57) | DDB1CRBNL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL18650 | 0.77 | LMNA (0.45) | DDB1CRBNNPC1RAB9AALDH1A1 | |
| SCHEMBL3021875 | 0.75 | DDB1 (0.55) | DDB1CRBNL3MBTL1ALDH1A1CYP3A4 | |
| SCHEMBL2706742 | 0.74 | DDB1 (0.47) | DDB1CRBNL3MBTL1NPC1RAB9A | |
| SCHEMBL15967719 | 0.74 | DDB1 (0.50) | DDB1CRBNL3MBTL1NPC1RAB9A | |
| SCHEMBL23135459 | 0.74 | ALDH1A1 (0.50) | DDB1CRBNL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3411381-B1 | C-3 AND C-17 MODIFIED TRITERPENOIDS AS HIV-1 INHIBITORS | VIIV HEALTHCARE UK NO 5 LTD (GB) | 2021-01-20 | — | — | EP | disclosed |
| WO-2017134596-A1 | C-3 AND C-17 MODIFIED TRITERPENOIDS AS HIV-1 INHIBITORS | VIIV Healthcare UK (No.5) Limited (GB) | 2017-08-10 | — | — | WO | disclosed |