SCHEMBL19259384

SCHEMBL19259384

CCCCCCC1(C)CCc2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 10/20 0.52
EBP Q15125 1/20 0.43
KDM1A O60341 1/20 0.41
LMNA P02545 1/20 0.41
OPRM1 P35372 1/20 0.40
OPRD1 P41143 1/20 0.40
OPRK1 P41145 1/20 0.40
OPRL1 P41146 1/20 0.40
ALDH1A1 P00352 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
CETP P11597 2/20 0.39
ALOX12 P18054 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22175918 0.98 SIGMAR1 (0.50) SIGMAR1EBPKDM1ALMNAALOX12
SCHEMBL7788011 0.82 SIGMAR1 (0.54) SIGMAR1EBPKDM1ALMNAOPRM1
SCHEMBL7782520 0.82 SIGMAR1 (0.54) SIGMAR1EBPKDM1ALMNAOPRM1
SCHEMBL7788022 0.82 SIGMAR1 (0.54) SIGMAR1EBPKDM1ALMNAOPRM1
SCHEMBL7782450 0.80 SIGMAR1 (0.51) SIGMAR1EBPKDM1ALMNAALDH1A1
Methyl Alcohol SCHEMBL14815579 0.80 SIGMAR1 (0.42) SIGMAR1KDM1ALMNAALDH1A1
SCHEMBL30411876 0.79 SIGMAR1 (0.51) SIGMAR1EBPKDM1ALMNAOPRM1
SCHEMBL7549093 0.79 SIGMAR1 (0.44) SIGMAR1EBPKDM1AALDH1A1CYP1A2
SCHEMBL30298333 0.79 SIGMAR1 (0.44) SIGMAR1EBPKDM1AALDH1A1CYP1A2
SCHEMBL30298335 0.79 SIGMAR1 (0.44) SIGMAR1EBPKDM1AALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3417033-B1 FORMULATION OF AN ORGANIC FUNCTIONAL MATERIAL MERCK PATENT GMBH (DE) 2021-02-24 EP disclosed
US-10840448-B2 Formulation of an organic functional material MERCK PATENT GMBH (DE) 2020-11-17 US disclosed
US-20190044067-A1 FORMULATION OF AN ORGANIC FUNCTIONAL MATERIAL MERCK PATENT GMBH (DE) 2019-02-07 US disclosed
EP-3417033-A1 FORMULATION OF AN ORGANIC FUNCTIONAL MATERIAL Merck Patent GmbH (DE) 2018-12-26 EP disclosed
WO-2017140404-A1 FORMULATION OF AN ORGANIC FUNCTIONAL MATERIAL MERCK PATENT GMBH (DE) 2017-08-24 WO disclosed