Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.45 |
| ▸ | EBP | Q15125 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782520 | 1.00 | SIGMAR1 (0.54) | SIGMAR1ESR2EBPKDM1AALDH1A1 | |
| SCHEMBL7788011 | 1.00 | SIGMAR1 (0.54) | SIGMAR1ESR2EBPKDM1AALDH1A1 | |
| SCHEMBL7782450 | 0.98 | SIGMAR1 (0.51) | SIGMAR1ESR2EBPKDM1AALDH1A1 | |
| SCHEMBL7788015 | 0.93 | SIGMAR1 (0.51) | SIGMAR1ESR2EBPKDM1ALMNA | |
| SCHEMBL28548755 | 0.90 | SIGMAR1 (0.56) | SIGMAR1EBPKDM1ACYP1A2CYP2C19 | |
| SCHEMBL28549243 | 0.90 | SIGMAR1 (0.56) | SIGMAR1EBPKDM1ACYP1A2CYP2C19 | |
| SCHEMBL28543963 | 0.90 | SIGMAR1 (0.56) | SIGMAR1EBPKDM1ACYP1A2CYP2C19 | |
| SCHEMBL11198839 | 0.90 | SIGMAR1 (0.56) | SIGMAR1EBPKDM1ACYP1A2CYP2C19 | |
| SCHEMBL7782464 | 0.86 | ESR2 (0.48) | SIGMAR1ESR2EBPKDM1ALMNA | |
| SCHEMBL11874561 | 0.85 | SIGMAR1 (0.44) | SIGMAR1ESR2EBPKDM1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010029286-A1 | Procatalysts, catalyst systems, and use in OLEFIN polymerization | EASTMAN CHEMICAL COMPANY, A CORP. OF DELAWARE | 2001-10-11 | — | — | US | disclosed |
| US-20010025005-A1 | Procatalysts, catalyst systems, and use in olefin polymerization | EASTMAN CHEMICAL COMPANY, A CORPORATION OF DELAWARE | 2001-09-27 | — | — | US | disclosed |
| WO-2001051527-A1 | PROCATALYSTS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |
| WO-2001051529-A1 | PROCATALYSTS COMPRISING BIDENTATE LIGANDS, CATALYST SYSTEMS, AND USE IN OLEFIN POLYMERIZATION | EASTMAN CHEMICAL COMPANY (US) | 2001-07-19 | — | — | WO | disclosed |