Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.51 |
| ▸ | CA2 | P00918 | 10/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3590172 | 0.85 | ALDH1A1 (0.55) | CA1CA2PKMCYP2A6GRM4 | |
| SCHEMBL3599576 | 0.78 | PKM (0.61) | CA1CA2PKMHTR6CA12 | |
| SCHEMBL2842158 | 0.77 | PKM (0.53) | PKMHTR6BRPF1SIRT6 | |
| SCHEMBL3427242 | 0.75 | CYP2A6 (0.50) | PKMCYP2A6GRM4HTR6CFTR | |
| SCHEMBL30720057 | 0.75 | CYP2A6 (0.50) | PKMCYP2A6GRM4HTR6CFTR | |
| SCHEMBL16381773 | 0.75 | CFTR (0.51) | PKMCYP2A6ALDH1A1CFTR | |
| SCHEMBL19260071 | 0.75 | CA1 (0.49) | CA1CA2GRM4BRPF1 | |
| SCHEMBL19329421 | 0.75 | PKM (0.51) | CA1CA2PKMHTR6ALDH1A1 | |
| SCHEMBL517089 | 0.75 | CYP2A6 (0.50) | CA1CA2PKMCYP2A6CA12 | |
| SCHEMBL13537281 | 0.74 | CYP2A6 (0.49) | PKMCYP2A6GRM4CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3416948-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | The University Of Queensland (AU) | 2018-12-26 | — | — | EP | disclosed |
| WO-2017140778-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-08-24 | — | — | WO | disclosed |