Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.56 |
| ▸ | APP | P05067 | 4/20 | 0.51 |
| ▸ | BACE1 | P56817 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | TRPM7 | Q96QT4 | 1/20 | 0.46 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19261676 | 0.93 | DHODH (0.54) | DHODHAPPBACE1PTPN1MAOB | |
| SCHEMBL15247914 | 0.88 | DHODH (0.60) | DHODHAPPBACE1PTPN1MAOB | |
| SCHEMBL29572464 | 0.87 | DHODH (0.71) | DHODHAPPBACE1PTPN1MAOB | |
| SCHEMBL2723348 | 0.87 | PTGES (0.61) | DHODHAPPBACE1PTPN1MAOB | |
| SCHEMBL15364116 | 0.85 | DHODH (0.69) | DHODHAPPBACE1PTPN1MAOB | |
| SCHEMBL15364121 | 0.85 | DHODH (0.69) | DHODHAPPBACE1PTPN1MAOB | |
| SCHEMBL15247881 | 0.82 | APP (0.67) | DHODHAPPBACE1PTPN1MAOB | |
| SCHEMBL15247901 | 0.81 | PTPN1 (0.52) | DHODHAPPBACE1PTPN1MAOB | |
| SCHEMBL16926180 | 0.81 | PTPN1 (0.52) | DHODHAPPBACE1PTPN1MAOB | |
| SCHEMBL15374666 | 0.78 | DHODH (0.73) | DHODHMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9737504-B2 | Dihydroorotic and acid dehydrogenase inhibitor | INSTITUTE OF MITOCHONDRIA SCIENCE, INC. (JP) | 2017-08-22 | — | — | US | disclosed |