Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.71 |
| ▸ | APP | P05067 | 3/20 | 0.64 |
| ▸ | BACE1 | P56817 | 2/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.63 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.54 |
| ▸ | PTGES | O14684 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | TRPM7 | Q96QT4 | 1/20 | 0.51 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15364116 | 0.99 | DHODH (0.69) | DHODHAPPBACE1PTPN1MAOB | |
| SCHEMBL15364121 | 0.99 | DHODH (0.69) | DHODHAPPBACE1PTPN1MAOB | |
| SCHEMBL15247914 | 0.91 | DHODH (0.60) | DHODHAPPBACE1PTPN1MAOB | |
| SCHEMBL2723348 | 0.90 | PTGES (0.61) | DHODHAPPBACE1PTPN1MAOB | |
| SCHEMBL19261658 | 0.87 | DHODH (0.56) | DHODHAPPBACE1PTPN1MAOB | |
| SCHEMBL15247881 | 0.85 | APP (0.67) | DHODHAPPBACE1PTPN1MAOB | |
| SCHEMBL19261676 | 0.85 | DHODH (0.54) | DHODHAPPBACE1PTPN1MAOB | |
| SCHEMBL16926180 | 0.82 | PTPN1 (0.52) | DHODHAPPBACE1PTPN1MAOB | |
| SCHEMBL15247901 | 0.82 | PTPN1 (0.52) | DHODHAPPBACE1PTPN1MAOB | |
| SCHEMBL15374666 | 0.81 | DHODH (0.73) | DHODHMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240150269-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | MCMASTER UNIVERSITY (CA) | 2024-05-09 | — | — | US | disclosed |
| US-11795127-B2 | Processes for the preparation of ortho-allylated hydroxy aryl compounds | MCMASTER UNIVERSITY (CA) | 2023-10-24 | — | — | US | disclosed |
| US-20230113567-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | MCMASTER UNIVERSITY (CA) | 2023-04-13 | — | — | US | disclosed |
| EP-4157811-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | McMaster University (CA) | 2023-04-05 | — | — | EP | disclosed |
| US-11512034-B2 | Processes for the preparation of ortho-allylated hydroxy aryl compounds | MCMASTER UNIVERSITY (CA) | 2022-11-29 | — | — | US | disclosed |
| US-11306317-B2 | Method of producing isoprenoids and proteins, genes, and transformants for the same | NAGASAKI UNIVERSITY (JP) | 2022-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230113567-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | ADH1A, ADH1C, AHR | DHODH 677/4885APP 1447/4885BACE1 2351/4885 |
| US-11795127-B2 | Processes for the preparation of ortho-allylated hydroxy aryl compounds | ADH1A, ADH1C, AHR | DHODH 677/4885APP 1447/4885BACE1 2351/4885 |
| US-11512034-B2 | Processes for the preparation of ortho-allylated hydroxy aryl compounds | ADH1A, ADH1C, AHR | DHODH 677/4885APP 1447/4885BACE1 2351/4885 |
| US-20240150269-A1 | PROCESSES FOR THE PREPARATION OF ORTHO-ALLYLATED HYDROXY ARYL COMPOUNDS | ADH1A, ADH1C, AHR | DHODH 776/4885APP 1679/4885BACE1 1851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.