Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | F2R | P25116 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13924990 | 0.85 | MEN1 (0.45) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL13904082 | 0.85 | MEN1 (0.45) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL19262173 | 0.77 | RAB9A (0.61) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL8209236 | 0.76 | MEN1 (0.60) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL12574796 | 0.76 | TDP1 (0.62) | SMN1; SMN2ALDH1A1KMT2ARXFP1L3MBTL1 | |
| SCHEMBL11866935 | 0.76 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL26386086 | 0.76 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL13391043 | 0.76 | HSD17B10 (0.67) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL2735680 | 0.76 | HSD17B10 (0.65) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL2384797 | 0.76 | ALDH1A1 (0.65) | SMN1; SMN2LMNAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738064-B2 | Lithographic printing plate precursor | AGFA GRAPHICS N.V. (BE) | 2017-08-22 | — | — | US | disclosed |