SCHEMBL19262201

SCHEMBL19262201

CNC(=O)OC(C)(C)CCOC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 2/20 0.33
CHRNA4 P43681 2/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33
CYP2D6 P10635 1/20 0.33
CHRM1 P11229 1/20 0.33
NFKB1 P19838 1/20 0.33
CHRM3 P20309 1/20 0.33
MAPK1 P28482 1/20 0.33
CHRNA7 P36544 1/20 0.33
TDP1 Q9NUW8 3/20 0.33
LMNA P02545 1/20 0.32
APEX1 P27695 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
EPHX1 P07099 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19262235 0.85 CHRM2 (0.32) CHRNB2CHRNA4CHRM2CHRM4CHRM5
SCHEMBL12111393 0.78 DGAT1 (0.33) MAPK1
SCHEMBL14520407 0.78 TDP1 (0.35) CHRNB2CHRNA4CHRM2CHRM4CHRM5
SCHEMBL21912604 0.78 TDP1 (0.36) CHRNB2CHRNA4CHRM2CHRM4CHRM5
SCHEMBL12259926 0.78 GAA (0.31)
SCHEMBL21555594 0.76 DGAT1 (0.30)
SCHEMBL12168462 0.76 LMNA (0.34) LMNAHSD17B10
SCHEMBL1669682 0.76 GAA (0.30)
SCHEMBL25767212 0.75 TDP1 (0.37) TDP1EPHX1ALDH1A1
SCHEMBL23015471 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11567404-B2 Lithographic printing plate precursor, method for making lithographic printing plate, organic polymer particle, and photosensitive resin composition FUJIFILM CORPORATION (JP) 2023-01-31 US disclosed
US-20200110336-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR MAKING LITHOGRAPHIC PRINTING PLATE, ORGANIC POLYMER PARTICLE, AND PHOTOSENSITIVE RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2020-04-09 US disclosed
US-20190023921-A1 AQUEOUS DISPERSION, METHOD FOR MANUFACTURING THE SAME, AND IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2019-01-24 US disclosed
US-9737607-B2 Polymer, and pharmaceutical composition employing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-08-22 US disclosed