Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19263024 | 0.87 | EPHX2 (0.60) | HDAC1HDAC8HDAC6HDAC5POLB | |
| SCHEMBL19263057 | 0.85 | POLB (0.66) | HDAC1HDAC8HDAC6HDAC5POLB | |
| SCHEMBL6407634 | 0.85 | POLB (0.53) | HDAC1HDAC8HDAC6HDAC5POLB | |
| SCHEMBL19263303 | 0.85 | HDAC1 (0.44) | HDAC1HDAC8HDAC6HDAC5POLB | |
| SCHEMBL19263070 | 0.85 | ALDH1A1 (0.51) | POLBSMN1; SMN2ALDH1A1HTTJAK2 | |
| SCHEMBL6404231 | 0.84 | POLB (0.52) | HDAC1HDAC8HDAC6HDAC5POLB | |
| SCHEMBL19263018 | 0.83 | POLB (0.48) | HDAC1HDAC8POLBEPHX2SMN1; SMN2 | |
| SCHEMBL19263069 | 0.83 | POLB (0.51) | HDAC1HDAC8HDAC6HDAC5POLB | |
| SCHEMBL6403386 | 0.83 | POLB (0.53) | HDAC1HDAC8HDAC6HDAC5POLB | |
| SCHEMBL19263020 | 0.82 | SMN1; SMN2 (0.69) | POLBSMN1; SMN2ALDH1A1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738673-B1 | Ferrocene derivative, preparation method and use thereof | XIAMEN INSTITUTE OF RARE EARTH MATERIALS (CN) | 2017-08-22 | — | — | US | disclosed |