Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404231 | 0.99 | POLB (0.52) | POLBSMN1; SMN2CYP1A2LMNAALDH1A1 | |
| SCHEMBL6403386 | 0.98 | POLB (0.53) | POLBSMN1; SMN2CYP1A2LMNAALDH1A1 | |
| SCHEMBL19263069 | 0.88 | POLB (0.51) | POLBSMN1; SMN2CYP1A2LMNAALDH1A1 | |
| SCHEMBL19263024 | 0.88 | EPHX2 (0.60) | POLBSMN1; SMN2CYP1A2LMNAALDH1A1 | |
| SCHEMBL19263057 | 0.88 | POLB (0.66) | POLBSMN1; SMN2CYP1A2LMNAALDH1A1 | |
| SCHEMBL19263070 | 0.88 | ALDH1A1 (0.51) | POLBSMN1; SMN2CYP1A2LMNAALDH1A1 | |
| SCHEMBL19263020 | 0.87 | SMN1; SMN2 (0.69) | POLBSMN1; SMN2CYP1A2LMNAALDH1A1 | |
| SCHEMBL19263258 | 0.85 | HDAC1 (0.53) | POLBSMN1; SMN2CYP1A2LMNAALDH1A1 | |
| SCHEMBL19263028 | 0.85 | POLB (0.47) | POLBSMN1; SMN2CYP1A2LMNAALDH1A1 | |
| SCHEMBL19263282 | 0.85 | POLB (0.41) | POLBSMN1; SMN2CYP1A2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738673-B1 | Ferrocene derivative, preparation method and use thereof | XIAMEN INSTITUTE OF RARE EARTH MATERIALS (CN) | 2017-08-22 | — | — | US | disclosed |
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | POLB 3713/4885SMN1; SMN2 4458/4885CYP1A2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.