Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 4/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | YES1 | P07947 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.31 |
| ▸ | LTK | P29376 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534692 | 0.88 | ALDH1A1 (0.36) | HPGDSALDH1A1HPGDF2GLA | |
| SCHEMBL14763588 | 0.88 | ALDH1A1 (0.49) | HPGDSALDH1A1HPGDF2GLA | |
| SCHEMBL13077864 | 0.88 | HPGDS (0.39) | HPGDSALDH1A1HPGDF2GLA | |
| SCHEMBL534791 | 0.87 | ALDH1A1 (0.33) | HPGDSALDH1A1HPGDF2GLA | |
| SCHEMBL534790 | 0.87 | ALDH1A1 (0.33) | HPGDSALDH1A1HPGDF2GLA | |
| SCHEMBL633389 | 0.87 | HPGDS (0.38) | HPGDSALDH1A1HPGDF2GLA | |
| SCHEMBL12181860 | 0.86 | PPARA (0.40) | HPGDSALDH1A1HPGDF2GLA | |
| SCHEMBL534690 | 0.85 | ALDH1A1 (0.34) | HPGDSALDH1A1HPGDF2GLA | |
| SCHEMBL534691 | 0.85 | ALDH1A1 (0.34) | HPGDSALDH1A1HPGDF2GLA | |
| SCHEMBL13077465 | 0.85 | SCN9A (0.39) | HPGDSALDH1A1HPGDF2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7956188-B2 | N-substituted-2-alkylthio-2-(substituted aryloxy and heteroaryloxy)alkylamides and their sulphinyl and sulphonyl derivatives such as 2-(3,5-dichlorophenoxy)-2-methylthio-N-2-methylprop-2-yl acetamide; fungal infections of plants | SYNGENTA CROP PROTECTION, INC. (US) | 2011-06-07 | — | — | US | disclosed |
| US-20100056570-A1 | FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-03-04 | — | — | US | disclosed |
| EP-1817309-B1 | ACETAMIDE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-12-23 | — | — | EP | disclosed |
| EP-2068632-A1 | FUNGICIDES | Syngeta Participations AG (CH) | 2009-06-17 | — | — | EP | disclosed |
| US-20080171767-A1 | N-substituted-2-alkylthio-2-(substituted aryloxy and heteroaryloxy)alkylamides and their sulphinyl and sulphonyl derivatives such as 2-(3,5-dichlorophenoxy)-2-methylthio-N-2-methylprop-2-yl acetamide; fungal infections of plants | SYNGENTA CROP PROTECTION, INC. (US) | 2008-07-17 | — | — | US | disclosed |
| WO-2008028624-A1 | FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171767-A1 | N-substituted-2-alkylthio-2-(substituted aryloxy and heteroaryloxy)alkylamides and their sulphinyl and sulphonyl derivatives such as 2-(3,5-dichlorophenoxy)-2-methylthio-N-2-methylprop-2-yl acetamide; fungal infections of plants | NAT1, DPM1, AADAC | HPGDS 4483/4885ALDH1A1 895/4885HPGD 4169/4885 |
| US-20100056570-A1 | FUNGICIDES | CYP21A2, CYP51A1, CYP4X1 | HPGDS 4806/4885ALDH1A1 336/4885HPGD 3810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.