Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Serine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | GLUL | P15104 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.45 |
| ▸ | GRM6 | O15303 | 1/20 | 0.45 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Serine SCHEMBL192644 | 1.00 | SLC1A1 (0.50) | SLC1A1GLULPTGS1SLC7A11GRM8 | |
| Serine SCHEMBL17927566 | 1.00 | SLC1A1 (0.50) | SLC1A1GLULPTGS1SLC7A11GRM8 | |
| Serine SCHEMBL27765657 | 0.97 | SLC1A1 (0.48) | SLC1A1GLULPTGS1SLC7A11GRM8 | |
| Serine SCHEMBL17187316 | 0.92 | SLC1A1 (0.48) | SLC1A1GLULPTGS1SLC7A11GRM8 | |
| Serine SCHEMBL9167560 | 0.90 | PTGS1 (0.48) | SLC1A1GLULPTGS1SLC7A11GRM8 | |
| Serine SCHEMBL1332181 | 0.89 | — | — | |
| Serine SCHEMBL6929773 | 0.89 | SLC1A1 (0.59) | SLC1A1PTGS1SLC7A11GRM8GRM6 | |
| (D)-Serine SCHEMBL43094 | 0.89 | — | — | |
| (D)-Serine SCHEMBL6660617 | 0.89 | SLC1A1 (0.59) | SLC1A1PTGS1SLC7A11GRM8GRM6 | |
| Serine SCHEMBL6520912 | 0.89 | SLC1A1 (0.59) | SLC1A1PTGS1SLC7A11GRM8GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118688315-A | Multichannel high-coverage synchronous quantification method for amino-containing and hydroxyl-containing compounds | 复旦大学 | 2024-09-24 | — | — | CN | claimed |
| CN-116735770-A | Synchronous quantitative detection method for multiple metabolites in biological sample | 复旦大学 | 2023-09-12 | — | — | CN | claimed |
| CN-109640633-A | Plant, the manufacturing method of plant, resistance adding method, tomato and tomato manufacturing method | 积水化学工业株式会社 | 2019-04-16 | — | — | CN | claimed |
| CN-104643067-B | Nutritional emulsions comprising HMB calcium and soluble protein | 雅培制药有限公司 | 2018-02-06 | — | — | CN | claimed |
| CN-107080236-A | Plastics packed nutrient solution comprising HMB | 雅培制药有限公司 | 2017-08-22 | — | — | CN | claimed |
| CN-103096736-B | Comprise the nutrient liquid of the substantially transparent of HMB calcium and soluble protein | ABBOTT LABORATORIES (US) | 2015-10-07 | — | — | CN | claimed |
| CN-102711522-B | Aseptically packaged nutritional liquids comprising HMB | ABBOTT LABORATORIES (US) | 2015-09-09 | — | — | CN | claimed |
| CN-104643067-A | Nutritional emulsions comprising calcium HMB and soluble protein | ABBOTT LAB | 2015-05-27 | — | — | CN | claimed |
| CN-102711525-B | Nutritional emulsions comprising calcium HMB and soluble protein | ABBOTT LAB | 2015-03-11 | — | — | CN | claimed |
| CN-102711524-B | Nutritional emulsions comprising calcium HMB | ABBOTT LAB | 2014-09-10 | — | — | CN | claimed |
| CN-102711524-A | Nutritional emulsions comprising calcium hmb | ABBOTT LAB | 2012-10-03 | — | — | CN | claimed |
| CN-102711522-A | Aseptically packaged nutritional liquids comprising HMB | ABBOTT LAB | 2012-10-03 | — | — | CN | claimed |
| US-8258117-B2 | Composition and method for the repair and regeneration of cartilage and other tissues | Piramal Healthcare (Canada) Ltd (CA) | 2012-09-04 | — | — | US | claimed |
| US-20110086008-A1 | COMPOSITION AND METHOD FOR THE REPAIR AND REGENERATION OF CARTILAGE AND OTHER TISSUES | SMITH & NEPHEW ORTHOPAEDICS AG (CH) | 2011-04-14 | — | — | US | claimed |
| US-7148209-B2 | Composition and method for the repair and regeneration of cartilage and other tissues | ECOLE POLYTECHNIQUE (CA) | 2006-12-12 | — | — | US | claimed |
| EP-1294414-B1 | COMPOSITION AND METHOD FOR THE REPAIR AND REGENERATION OF CARTILAGE AND OTHER TISSUES | BIOSYNTECH CANADA INC (CA) | 2006-03-15 | — | — | EP | claimed |
| US-20060029578-A1 | Composition and method for the repair and regeneration of cartilage and other tissues | ECOLE POLYTECHNIQUE | 2006-02-09 | — | — | US | claimed |
| EP-1294414-A2 | COMPOSITION AND METHOD FOR THE REPAIR AND REGENERATION OF CARTILAGE AND OTHER TISSUES | Biosyntech Canada Inc. (CA) | 2003-03-26 | — | — | EP | claimed |
| US-20020082220-A1 | Composition and method for the repair and regeneration of cartilage and other tissues | PIRAMAL HEALTHCARE (CANADA) LTS. (CA) | 2002-06-27 | — | — | US | claimed |
| WO-2002000272-A2 | COMPOSITION AND METHOD FOR THE REPAIR AND REGENERATION OF CARTILAGE AND OTHER TISSUES | BIOSYNTECH CANADA INC. (CA) | 2002-01-03 | — | — | WO | claimed |