Serine

Serine

SCHEMBL192644

NC(CO)C(=O)O.O=P(O)(O)O

nearest known ligand 0.52

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Serine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC1A1 P43005 1/20 0.50
GLUL P15104 1/20 0.47
PTGS1 P23219 1/20 0.46
SLC7A11 Q9UPY5 1/20 0.46
GRM8 O00222 1/20 0.45
GRM6 O15303 1/20 0.45
GRM7 Q14831 1/20 0.45
GRM4 Q14833 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Serine SCHEMBL192645 1.00 SLC1A1 (0.50) SLC1A1GLULPTGS1SLC7A11GRM8
Serine SCHEMBL17927566 1.00 SLC1A1 (0.50) SLC1A1GLULPTGS1SLC7A11GRM8
Serine SCHEMBL27765657 0.97 SLC1A1 (0.48) SLC1A1GLULPTGS1SLC7A11GRM8
Serine SCHEMBL17187316 0.92 SLC1A1 (0.48) SLC1A1GLULPTGS1SLC7A11GRM8
Serine SCHEMBL9167560 0.90 PTGS1 (0.48) SLC1A1GLULPTGS1SLC7A11GRM8
Serine SCHEMBL1332181 0.89
Serine SCHEMBL6929773 0.89 SLC1A1 (0.59) SLC1A1PTGS1SLC7A11GRM8GRM6
(D)-Serine SCHEMBL43094 0.89
(D)-Serine SCHEMBL6660617 0.89 SLC1A1 (0.59) SLC1A1PTGS1SLC7A11GRM8GRM6
Serine SCHEMBL6520912 0.89 SLC1A1 (0.59) SLC1A1PTGS1SLC7A11GRM8GRM6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075784-A Bionic bone with controllable solidification time and preparation method and application thereof 2026-05-26 CN claimed
CN-115397247-B Fermented milk, process for producing the same, and dephosphorized yogurt GODO SHUSEI Co.,Ltd. (JP) 2026-05-26 CN claimed
CN-120078927-A High-strength low-immune-response bone adhesive material and preparation and application methods thereof 杭州源囊生物科技有限公司 2025-06-03 CN claimed
CN-115804861-B Bone adhesive solid phase composition and bone adhesive 北京纳通医学研究院有限公司 2024-06-14 CN claimed
CN-117338992-A Bone adhesive and preparation method thereof 上海瑞凝生物科技有限公司 2024-01-05 CN claimed
CN-113624862-B Metabolome covering multiple metabolites, metabolic flux analysis method and kit 清华大学 2023-04-07 CN claimed
CN-115804861-A Bone adhesive solid-phase composition and bone adhesive 北京纳通医学研究院有限公司 2023-03-17 CN claimed
CN-109640633-A Plant, the manufacturing method of plant, resistance adding method, tomato and tomato manufacturing method 积水化学工业株式会社 2019-04-16 CN claimed
CN-108201635-A Bone Defect Repari stent under a kind of articular cartilage 重庆润泽医药有限公司 2018-06-26 CN claimed
CN-104643067-B Nutritional emulsions comprising HMB calcium and soluble protein 雅培制药有限公司 2018-02-06 CN claimed
CN-103025360-A Reinforced adhesive complex coacervates and methods of making and using thereof UNIV UTAH RES FOUND 2013-04-03 CN claimed
CN-102762112-A Plastic packaged nutritional liquids comprising HMB ABBOTT LAB 2012-10-31 CN claimed
CN-102711522-A Aseptically packaged nutritional liquids comprising HMB ABBOTT LAB 2012-10-03 CN claimed
CN-102711525-A Nutritional emulsions comprising calcium HMB and soluble protein ABBOTT LAB 2012-10-03 CN claimed
CN-102711524-A Nutritional emulsions comprising calcium hmb ABBOTT LAB 2012-10-03 CN claimed
CN-101978040-A Adhesive complex coacervates and methods of making and using the same UNIV UTAH RES FOUDATION (US) 2011-02-16 CN claimed
US-20040180381-A1 Method for determining amino acid sequence of a peptide SHIMADZU CORPORATION (JP) 2004-09-16 US claimed
EP-1361872-A4 NOVEL LYSOPHOSPHATIDIC ACID RECEPTOR AGONISTS AND ANTAGONISTS UNIV VIRGINIA (US) 2004-05-19 EP claimed
EP-1361872-A2 NOVEL LYSOPHOSPHATIDIC ACID RECEPTOR AGONISTS AND ANTAGONISTS UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2003-11-19 EP claimed
WO-2002029001-A2 NOVEL LYSOPHOSPHATIDIC ACID RECEPTOR AGONISTS AND ANTAGONISTS UNIVERSITY OF VIRGINIAN PATENT FOUNDATION (US) 2002-04-11 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040180381-A1 Method for determining amino acid sequence of a peptide VIP, ANPEP, DNPEP SLC1A1 910/4885GLUL 218/4885PTGS1 4440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.