Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14216841 | 1.00 | L3MBTL1 (0.34) | L3MBTL1GAAPOLBHSD17B10RAB9A | |
| SCHEMBL20249096 | 0.86 | L3MBTL1 (0.36) | L3MBTL1GAAPOLBHSD17B10RAB9A | |
| SCHEMBL23961369 | 0.79 | SLC6A3 (0.36) | L3MBTL1GAAPOLBHSD17B10RAB9A | |
| SCHEMBL22414058 | 0.78 | SLC6A3 (0.38) | L3MBTL1GAAPOLBHSD17B10RAB9A | |
| SCHEMBL28824409 | 0.77 | SMN1; SMN2 (0.35) | L3MBTL1GAAPOLBHSD17B10RAB9A | |
| SCHEMBL12119805 | 0.75 | — | — | |
| SCHEMBL1188560 | 0.75 | HPGD (0.38) | L3MBTL1GAAPOLBHSD17B10RAB9A | |
| SCHEMBL482624 | 0.75 | — | — | |
| SCHEMBL10030794 | 0.75 | — | — | |
| SCHEMBL12384607 | 0.73 | HPGD (0.35) | L3MBTL1GAAPOLBHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3208269-A1 | INHIBITORS OF C-FMS KINASE | Janssen Pharmaceutica N.V. (BE) | 2017-08-23 | — | — | EP | disclosed |