Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 16/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23861660 | 0.74 | TLR8 (0.58) | TLR8KDM4EALDH1A1HPGDGAA | |
| SCHEMBL1118532 | 0.70 | ALDH1A1 (0.53) | TLR8KDM4EALDH1A1HPGDGAA | |
| SCHEMBL16836317 | 0.70 | TLR8 (0.65) | TLR8KDM4EALDH1A1HPGDGAA | |
| SCHEMBL16836321 | 0.70 | TLR8 (0.74) | TLR8TLR7 | |
| SCHEMBL28158705 | 0.70 | TLR8 (0.56) | TLR8KDM4EALDH1A1HPGDGAA | |
| SCHEMBL14001902 | 0.70 | HSD17B10 (0.52) | TLR8KDM4EALDH1A1HPGDGAA | |
| SCHEMBL18593898 | 0.70 | TLR8 (0.68) | TLR8TLR7 | |
| SCHEMBL6833669 | 0.69 | ALDH1A1 (0.61) | TLR8KDM4EALDH1A1HPGDGAA | |
| SCHEMBL28282506 | 0.69 | TLR8 (0.53) | TLR8ALDH1A1TLR7CYP1A2TDP1 | |
| SCHEMBL16836314 | 0.68 | TLR8 (0.79) | TLR8KDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3208263-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VentiRx Pharmaceuticals, Inc. (US) | 2017-08-23 | — | — | EP | disclosed |