Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.55 |
| ▸ | TUBB | P07437 | 3/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.55 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.55 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.55 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.55 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.55 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20538477 | 0.93 | KDM1A (0.68) | KDM1ABCHETUBB1TUBB4ATUBB | |
| SCHEMBL20538479 | 0.93 | KDM1A (0.68) | KDM1ABCHETUBB1TUBB4ATUBB | |
| SCHEMBL20537858 | 0.91 | KDM1A (0.72) | KDM1ABCHETUBB1TUBB4ATUBB | |
| SCHEMBL20537857 | 0.91 | KDM1A (0.72) | KDM1ABCHETUBB1TUBB4ATUBB | |
| SCHEMBL19275931 | 0.91 | BCHE (0.59) | KDM1ABCHETUBB1TUBB4ATUBB | |
| SCHEMBL19275929 | 0.90 | TUBB1 (0.60) | BCHETUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL20538508 | 0.89 | MMP1 (0.67) | KDM1ABCHETUBB1TUBB4ATUBB | |
| SCHEMBL20537840 | 0.89 | KDM1A (0.64) | KDM1ABCHETUBB1TUBB4ATUBB | |
| SCHEMBL20538510 | 0.89 | MMP1 (0.67) | KDM1ABCHETUBB1TUBB4ATUBB | |
| SCHEMBL19800983 | 0.89 | KDM1A (0.64) | KDM1ABCHETUBB1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9878977-B2 | N-((3,4,5-trimethoxystyryl)aryl)cinnamamide compounds as potential anticancer agents and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-01-30 | — | — | US | disclosed |
| US-20170240503-A1 | N-((3,4,5-TRIMETHOXYSTYRYL)ARYL)CINNAMAMIDE COMPOUNDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2017-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170240503-A1 | N-((3,4,5-TRIMETHOXYSTYRYL)ARYL)CINNAMAMIDE COMPOUNDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CYP51A1, CBR3 | KDM1A 1609/4885BCHE 3267/4885TUBB1 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.