Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.60 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.60 |
| ▸ | TUBB | P07437 | 6/20 | 0.60 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.60 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.60 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.60 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.60 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.60 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.60 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.60 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.60 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.60 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.60 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.60 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20537851 | 0.92 | TUBB4A (0.65) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20537855 | 0.92 | TUBB4A (0.65) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19275927 | 0.91 | TUBB1 (0.58) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19275928 | 0.90 | KDM1A (0.59) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19801001 | 0.90 | TUBB4A (0.63) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20538418 | 0.90 | TUBB4A (0.63) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19275930 | 0.90 | ALDH1A1 (0.57) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19275931 | 0.88 | BCHE (0.59) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20538218 | 0.87 | KDM1A (0.67) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL20537644 | 0.87 | TUBB4A (0.66) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9878977-B2 | N-((3,4,5-trimethoxystyryl)aryl)cinnamamide compounds as potential anticancer agents and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-01-30 | — | — | US | disclosed |
| US-20170240503-A1 | N-((3,4,5-TRIMETHOXYSTYRYL)ARYL)CINNAMAMIDE COMPOUNDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2017-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170240503-A1 | N-((3,4,5-TRIMETHOXYSTYRYL)ARYL)CINNAMAMIDE COMPOUNDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CYP51A1, CBR3 | TUBB1 286/4885TUBB4A 147/4885TUBB 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.