Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24161892 | 0.94 | TNKS2 (0.43) | TNKS2PTPN11KDM4ECA12CA1 | |
| SCHEMBL17655667 | 0.86 | KDM4E (0.57) | TNKS2PTPN11KDM4ECA12CA1 | |
| SCHEMBL19276925 | 0.86 | KDM4E (0.54) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL19272079 | 0.80 | LMNA (0.68) | TNKS2PTPN11KDM4ECA12CA1 | |
| SCHEMBL22824418 | 0.80 | KDM4E (0.65) | TNKS2PTPN11KDM4ECA12CA1 | |
| SCHEMBL20693295 | 0.79 | TSHR (0.48) | PTPN11KDM4ECA12CA1CA2 | |
| Syringate SCHEMBL159392 | 0.78 | CA12 (0.67) | PTPN11KDM4ECA12CA1CA2 | |
| SCHEMBL4652561 | 0.76 | CA12 (0.57) | KDM4ECA12CA1CA2CA7 | |
| SCHEMBL28325906 | 0.76 | AKR1B1 (0.52) | TNKS2KDM4ECA12CA1CA2 | |
| SCHEMBL29245495 | 0.75 | PKM (0.60) | KDM4ECA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190032098-A1 | PROCESS FOR PREPARING BIPHENYL COMPOUNDS | UNIV BORDEAUX (FR) | 2019-01-31 | — | — | US | disclosed |
| US-20170240937-A1 | NEW PROCESS FOR PREPARING BIPHENYL COMPOUNDS | UNIVERSITÉ DE BORDEAUX (FR) | 2017-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190032098-A1 | PROCESS FOR PREPARING BIPHENYL COMPOUNDS | CYP1B1, CYP1A1, CYP1A2 | TNKS2 3511/4885PTPN11 3832/4885KDM4E 1298/4885 |
| US-20170240937-A1 | NEW PROCESS FOR PREPARING BIPHENYL COMPOUNDS | CYP1B1, CYP1A1, CYP1A2 | TNKS2 3352/4885PTPN11 3709/4885KDM4E 1044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.